Make sure you have exactlly four grenades on you. Toss two simultaneously at El Gigante and he will go on his knees. If you leap off of him toss two far more grenades speedily and soar on him. He will die in at the least 30 seconds or much less. http://claytonnwcio.blogpostie.com/8468497/resident-evil-4-unlockables-an-overview